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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
YES1
All Species:
13.64
Human Site:
Y159
Identified Species:
30
UniProt:
P07947
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07947
NP_005424.1
543
60801
Y159
S
I
Q
A
E
E
W
Y
F
G
K
M
G
R
K
Chimpanzee
Pan troglodytes
XP_001147665
576
64512
Y159
S
I
Q
A
E
E
W
Y
F
G
K
M
G
R
K
Rhesus Macaque
Macaca mulatta
XP_001087926
543
60741
Y159
S
I
Q
A
E
E
W
Y
F
G
K
M
G
R
K
Dog
Lupus familis
XP_547654
541
60616
G159
Q
A
E
E
W
Y
F
G
K
M
G
R
K
D
A
Cat
Felis silvestris
Mouse
Mus musculus
Q04736
541
60612
G159
Q
A
E
E
W
Y
F
G
K
M
G
R
K
D
A
Rat
Rattus norvegicus
Q9WUD9
536
60060
R163
I
T
R
R
E
S
E
R
L
L
L
N
A
E
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508295
452
51612
I123
D
N
V
K
H
Y
K
I
R
K
L
D
N
G
G
Chicken
Gallus gallus
P09324
541
60774
G159
Q
A
E
E
W
Y
F
G
K
M
G
R
K
D
A
Frog
Xenopus laevis
P10936
537
60339
R159
W
Y
F
G
K
M
G
R
K
D
A
E
R
L
L
Zebra Danio
Brachydanio rerio
NP_001013288
546
61250
Y162
S
I
Q
A
E
E
W
Y
F
G
K
M
G
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V9J3
517
59051
E160
A
F
L
I
R
D
S
E
S
R
H
N
D
Y
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.2
99.6
97.6
N.A.
95.9
73.6
N.A.
81.4
91.9
89.6
85.9
N.A.
54.3
N.A.
N.A.
N.A.
Protein Similarity:
100
94.2
99.8
97.9
N.A.
97
83.2
N.A.
82.6
96.3
93.7
91.3
N.A.
67.2
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
0
6.6
N.A.
0
0
0
100
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
13.3
13.3
N.A.
0
13.3
6.6
100
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
28
0
37
0
0
0
0
0
0
10
0
10
0
28
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
10
0
0
0
10
0
10
10
28
0
% D
% Glu:
0
0
28
28
46
37
10
10
0
0
0
10
0
10
0
% E
% Phe:
0
10
10
0
0
0
28
0
37
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
0
10
28
0
37
28
0
37
10
10
% G
% His:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
10
37
0
10
0
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
10
0
10
0
37
10
37
0
28
0
37
% K
% Leu:
0
0
10
0
0
0
0
0
10
10
19
0
0
10
10
% L
% Met:
0
0
0
0
0
10
0
0
0
28
0
37
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
0
19
10
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
28
0
37
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
10
10
0
0
19
10
10
0
28
10
37
0
% R
% Ser:
37
0
0
0
0
10
10
0
10
0
0
0
0
0
10
% S
% Thr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
10
0
0
0
28
0
37
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
37
0
37
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _